Sex hormones predict joint replacement medical study 2014

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http://www.rheumatologyupdate.com.au/latest-news/sex-hormone-levels-predict-joint-replacement

April 2014 by Monash University and Alfred hospital

Women who have knee and hip replacements due to osteoarthritis (OA) have different patterns of sex hormone concentrations compared with the general population, according to Melbourne researchers.

Their prospective study of a cohort of over 2,600 middle-aged women with ten-year follow-up found that higher oestradiol concentrations reduced the risk of total knee replacement by about a third.

The finding was consistent with a previous study showing women using long-term postmenopausal oestrogen therapy had greater knee cartilage volume than non-users…