Hormone replacement therapy increases implant survival following hip arthroplasty for osteoarthritis study 2013

Full Text Available Here:  http://ard.bmj.com/content/early/2014/01/07/annrheumdis-2013-204043

Osteolysis and subsequent prosthesis loosening is the most common cause for revision following total knee arthroplasty (TKA) or total hip arthroplasty (THA). Hormone replacement therapy (HRT) could reduce osteolysis through its antiresorptive effects…

We matched 2700 HRT users to 8100 non-users, observed for a median (IQR) of 3.3 (1.5 – 6.1) years after TKA/THA. HR for HRT ≥6 months was 0.62 (95% CI 0.41 to 0.94), whereas HR for ≥12 months was 0.48 (0.29 to 0.78)…

…HRT use is associated with an almost 40% reduction in revision rates after a TKA/THA.